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Triclosan

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Test Parameter Specification
Description Fine, whitish, crystalline powder. Melts at about 57°C
Solubility Soluble in methanol, in alcohol and in acetone. Slightly soluble in hexane. Practically insoluble in water.
Identification by IR Absorption The IR absorption spectrum of the sample should be concordant with IR absorption spectrum of Triclosan working standard
Identification by GC RT The retention time of the major peak in the chromatogram of the Assay preparation should corresponds to that in the chromatogram of the standard preparation, as obtained in the Assay
Water Not more than 0.01%
Completeness Of Solution A solution of 1.40 g of triclosan in 10 ml of acetone is clear
Related Compounds by GC
  a. Any Individual Impurity
  b. Total Impurities
 
Not more than 0.1%
Not more than 0.1%
Phenolic Impurities by HPLC
  a. 4-Chlorophenol
  b. 2.4-Dichlorophenol
 
Not more than 50ppm
Not more than 10ppm
Neutral Impurities by HPLC
  a. 1.3.7-trichlorodibenzo-p-dioxin
  b. 2.8-trichlorodibenzo-p-dioxin
  c. 2.8-trichlorodibenzofuran
  d. 2.4.8-trichlorodibenzofuran
 
Not more than 0.25 ppm
Not more than 0.5 ppm
Not more than 0.25 ppm
Not more than 0.5 ppm
Neutral Impurities by GC-Mass
  a. 2.3.7.8-trichlorodibenzo-p-dioxin
  b. 2.3.7.8-trichlorodibenzofuran
 
Not more than 1.0 ppt
Not more than 1.0 ppt
Assay by GC ( on anhydrous basis ) Not less than 97.0% and not more than 103.0% w/w

Shelf Life: 5 years

Storage: To be stored in properly sealed and labeled containers in a clean and dry place with adequate ventilation. Sensitive to heat above temperature of 40° C. Keep away from chlorinating and oxidizing substances. Keep away from direct sunlight and heat.

Usage and application of Triclosan:
Triclosan is used in soaps, deodorants, toothpaste, shaving creams, mouthwashes and cleansing supplies and is included in an increasing number of consumer products.


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