Test Parameter | Specification |
Description | Fine, whitish, crystalline powder. Melts at about 57°C |
Solubility | Soluble in methanol, in alcohol and in acetone. Slightly soluble in hexane. Practically insoluble in water. |
Identification by IR Absorption | The IR absorption spectrum of the sample should be concordant with IR absorption spectrum of Triclosan working standard |
Identification by GC RT | The retention time of the major peak in the chromatogram of the Assay preparation should corresponds to that in the chromatogram of the standard preparation, as obtained in the Assay |
Water | Not more than 0.01% |
Completeness Of Solution | A solution of 1.40 g of triclosan in 10 ml of acetone is clear |
Related Compounds by GC a. Any Individual Impurity b. Total Impurities |
Not more than 0.1% Not more than 0.1% |
Phenolic Impurities by HPLC a. 4-Chlorophenol b. 2.4-Dichlorophenol |
Not more than 50ppm Not more than 10ppm |
Neutral Impurities by HPLC a. 1.3.7-trichlorodibenzo-p-dioxin b. 2.8-trichlorodibenzo-p-dioxin c. 2.8-trichlorodibenzofuran d. 2.4.8-trichlorodibenzofuran |
Not more than 0.25 ppm Not more than 0.5 ppm Not more than 0.25 ppm Not more than 0.5 ppm |
Neutral Impurities by GC-Mass a. 2.3.7.8-trichlorodibenzo-p-dioxin b. 2.3.7.8-trichlorodibenzofuran |
Not more than 1.0 ppt Not more than 1.0 ppt |
Assay by GC ( on anhydrous basis ) | Not less than 97.0% and not more than 103.0% w/w |
Shelf Life: 5 years
Storage: To be stored in properly sealed and labeled containers in a clean and dry place with adequate ventilation. Sensitive to heat above temperature of 40° C. Keep away from chlorinating and oxidizing substances. Keep away from direct sunlight and heat.
Usage and application of Triclosan:
Triclosan is used in soaps, deodorants, toothpaste, shaving creams, mouthwashes and cleansing supplies and is included in an increasing number of consumer products.